| | | Saturday, August 24th, 2013 | | Signed 2B Daniel Roberts to a 3-year contract extension worth a total of $27,000,000. |
| Saturday, July 27th, 2013 | | Signed LF Kazunori Mizuno to a 2-year contract extension worth a total of $2,000,000. | | Signed CL Stan Wardlow to a 3-year contract extension worth a total of $4,100,000. |
| Saturday, July 13th, 2013 | | Signed Josh Younger to a minor league contract with a signing bonus of $180,000. |
| Friday, July 5th, 2013 | | Signed Willie Brown to a minor league contract with a signing bonus of $6,660,000. |
| Thursday, June 20th, 2013 | | Signed MR Desi Moore to a 3-year contract extension worth a total of $11,800,000. |
| Monday, May 6th, 2013 | | Placed MR Issam Asukile on the 15-day disabled list. |
| Tuesday, April 16th, 2013 | | Placed LF Colin McKee on the 60-day disabled list. |
| Saturday, March 9th, 2013 | | Placed 2B Bill Beach on the 15-day disabled list. |
| Saturday, January 26th, 2013 | | Placed MR Issam Asukile on the active roster. |
| Monday, January 21st, 2013 | | Signed free agent MR James von Wilke to a 1-year contract worth a total of $730,000. |
| Wednesday, January 16th, 2013 | | Signed free agent MR Issam Asukile to a 1-year contract worth a total of $400,000. |
| Saturday, January 12th, 2013 | | Signed free agent SP Justin Standish to a 4-year contract worth a total of $22,880,000. |
| Saturday, December 1st, 2012 | | Traded 22-year-old left fielder José Cantú to the Charleston Cicadas, getting 27-year-old minor league starting pitcher Don Gibson and 25-year-old starting pitcher Luis Pérez in return. | | Placed SP Luis Pérez on the active roster. | | Purchased the contract of SP Don Gibson from Rookie League Waynesboro. | | Drafted 3B Joe McLaughlin in the 2012 Rule 5 Draft (Round 1, Pick 1, 1st overall Pick), from the Providence Steamrollers. | | Lost LF Andrés Ramos in the Rule 5 Draft to the Chula Vista Herders. | | Drafted SP Ken Austin in the 2012 Rule 5 Draft (Round 2, Pick 1, 31st overall Pick), from the Charleston Cicadas. | | Drafted SP Glenn Ray in the 2012 Rule 5 Draft (Round 3, Pick 1, 61st overall Pick), from the Youngstown Steelheads. |
| Sunday, November 18th, 2012 | | SP Keith Gratton becomes a free-agent. | | 2B Bill Beach received a 1-year contract through automatic renewal worth a total of $400,000. | | C Carl Poole received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Norm Yabsley becomes a free-agent. | | MR Paco Hesía received a 1-year contract through automatic renewal worth a total of $400,000. | | CL Colby Ewing received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Derek Beardall received a 1-year contract through automatic renewal worth a total of $400,000. | | LF José Cantú received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Gunnar Gallon received a 1-year contract through automatic renewal worth a total of $400,000. | | 3B Terry Houston received a 1-year contract through automatic renewal worth a total of $400,000. | | CF Vicente Barrón received a 1-year contract through automatic renewal worth a total of $400,000. | | 3B Alejandro Figueroa received a 1-year contract through automatic renewal worth a total of $400,000. |
| Thursday, November 15th, 2012 | | MR Andrew MacLeish becomes a free-agent. | | 1B Jon Smith received a 1-year contract through arbitration worth a total of $600,000. |
| Sunday, November 4th, 2012 | | Signed MR José Balbuena to a 2-year contract extension worth a total of $1,600,000. |
| Tuesday, October 30th, 2012 | | Signed RF William Copeland to a 2-year contract extension worth a total of $3,000,000. |
| Friday, October 26th, 2012 | | Signed SS Paul Callahan to a 1-year contract extension worth a total of $700,000. | | Signed MR Jeremy Gregg to a 1-year contract extension worth a total of $800,000. |
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