| Laredo Peril |  |
| | Player | Injury | Out for... | Disabled List Status | | P Owen Cherry | ruptured ulnar collateral ligament | 4 months | On DL, eligible for return |
| Manasquan Golden Bears |  |
| | Player | Injury | Out for... | Disabled List Status | | P Jong-yong Ch'oe | torn flexor tendon (elbow) | 6 months | Not on DL |
| Orlando Whirlwinds |  |
| | Player | Injury | Out for... | Disabled List Status | | P Dave MacGruder | torn UCL (Tommy John surgery) | 3 months | On DL, eligible for return |
| Piru Harriers |  |
| | Player | Injury | Out for... | Disabled List Status | | 2B Diego Lucero | viral infection | 4 days | Not on DL |
| Saint Paul Steeds |  |
| | Player | Injury | Out for... | Disabled List Status | | P Francisco Marín | torn elbow ligament | 3-4 months | On DL, eligible for return |
| Santa Ana Goths |  |
| | Player | Injury | Out for... | Disabled List Status | | P Brennan Blanton | torn UCL (Tommy John surgery) | 4 months | On DL, eligible for return |
| Taylorsville Cheyenne |  |
| | Player | Injury | Out for... | Disabled List Status | | 3B Víctor González | strained hamstring | 4 days | On DL, eligible for return |
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