| | | Wednesday, March 30th, 2016 | | Placed RF Wally Smith on the 15-day disabled list. |
| Monday, March 21st, 2016 | | Placed SS Joe Butler on the 15-day disabled list. |
| Monday, March 14th, 2016 | | Placed SP Esteban García on the 15-day disabled list. |
| Wednesday, January 6th, 2016 | | 2B Gustavo Díaz was designated for assignment and placed on waivers. | | Placed SP José Macías on the active roster. |
| Sunday, December 27th, 2015 | | Signed free agent SP José Macías to a 1-year contract worth a total of $880,000. |
| Saturday, December 12th, 2015 | | Signed free agent SP Jeremy Méndez to a 1-year contract worth a total of $690,000. |
| Thursday, December 10th, 2015 | | Signed free agent C Roberto Gonzáles to a 2-year contract worth a total of $3,180,000. |
| Tuesday, November 17th, 2015 | | 3B Moustafa Adebamgbe received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Ricardo Arellano received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Yunosuke Hori received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Woody Brewster received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Kelvin Moore received a 1-year contract through automatic renewal worth a total of $400,000. | | CF Scott Pearson received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Don Jenkins received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Sergio Gonzáles received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Joe Butler received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Wally Smith received a 1-year contract through automatic renewal worth a total of $400,000. | | CF Gilberto Ramírez received a 1-year contract through automatic renewal worth a total of $400,000. | | CL Dan Dodson becomes a free-agent. | | C Manuel Torres received a 1-year contract through automatic renewal worth a total of $400,000. | | 2B Gustavo Díaz received a 1-year contract through automatic renewal worth a total of $400,000. | | 2B Jeff Penn received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Vicente González received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Esteban García received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Brian Williams received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Victor Morris becomes a free-agent. | | CL Reginald Moore received a 1-year contract through automatic renewal worth a total of $400,000. | | CL José Pérez received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Manuel Ortíz received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Anthony Simon received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Bill McDaniel received a 1-year contract through automatic renewal worth a total of $400,000. | | C Carlos Campos becomes a free-agent. | | Purchased the contract of MR Arturo Sánchez from Triple A Akron. |
| Saturday, November 14th, 2015 | | CL Carlos Mata received a 1-year contract through arbitration worth a total of $600,000. | | SP Oliver Noriega received a 1-year contract through arbitration worth a total of $3,000,000. | | C Dave Connolly received a 1-year contract through arbitration worth a total of $800,000. | | MR Dan Thompson received a 1-year contract through arbitration worth a total of $600,000. | | LF James Lee received a 1-year contract through arbitration worth a total of $600,000. | | CL Álex Betacourt received a 1-year contract through arbitration worth a total of $600,000. | | 2B José Trejo received a 1-year contract through arbitration worth a total of $750,000. | | 1B Alfonso De Jesús received a 1-year contract through arbitration worth a total of $3,800,000. | | MR Fernando Féliz received a 1-year contract through arbitration worth a total of $600,000. | | SP Dalton Henry received a 1-year contract through arbitration worth a total of $1,504,000. | | 3B Josh McKinney received a 1-year contract through arbitration worth a total of $850,000. |
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