| | | Thursday, April 14th, 2016 | | Signed free agent MR Jack Brooks to a 1-year contract worth a total of $610,000. | | Signed free agent C Michael Henry to a minor league contract. |
| Wednesday, March 23rd, 2016 | | Signed free agent MR Rafael Aguilar to a minor league contract. |
| Monday, March 14th, 2016 | | Placed SS Julián Rodríguez on the 15-day disabled list. |
| Tuesday, March 1st, 2016 | | Signed free agent C Carl Thomas to a minor league contract. |
| Saturday, February 27th, 2016 | | Signed free agent SS Anastasio Vargas to a minor league contract. |
| Saturday, February 13th, 2016 | | Signed free agent SP José Fernández to a 1-year contract worth a total of $5,000,000. | | Signed free agent LF Mauro Montoya to a minor league contract. |
| Monday, February 1st, 2016 | | Signed free agent MR Sergio Ruíz to a 1-year contract worth a total of $630,000. | | Signed free agent MR Luke Stuckey to a 3-year contract worth a total of $5,280,000. | | Placed MR Sergio Ruíz on the 40-man roster. | | Placed MR Sergio Ruíz on the active roster. |
| Thursday, January 21st, 2016 | | Signed free agent LF Patrick Gould to a minor league contract. |
| Tuesday, January 19th, 2016 | | Signed free agent RF Adam Gravelle to a 1-year contract worth a total of $950,000. |
| Saturday, January 16th, 2016 | | Signed free agent MR Esteban Francisco to a 1-year contract worth a total of $600,000. |
| Saturday, January 9th, 2016 | | Signed free agent MR Francisco Alemán to a 1-year contract worth a total of $540,000. |
| Saturday, December 26th, 2015 | | Signed free agent 1B Jorge Acosta to a 1-year contract worth a total of $1,180,000. |
| Thursday, December 24th, 2015 | | Signed free agent MR Jong-yong Ch'oe to a minor league contract. |
| Thursday, December 10th, 2015 | | Signed free agent CL Guignard Castano to a minor league contract. |
| Tuesday, December 8th, 2015 | | Signed free agent SP Ben Martin to a minor league contract. |
| Tuesday, November 17th, 2015 | | SP Esteban Hernández received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Rod Marshall received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Julián Rodríguez received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Eduardo Sánchez received a 1-year contract through automatic renewal worth a total of $400,000. | | CF Masamichi Kaneko received a 1-year contract through automatic renewal worth a total of $400,000. | | SP David Trujillo becomes a free-agent. | | LF Ryan Hankins received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Hang-yu Song received a 1-year contract through automatic renewal worth a total of $400,000. | | MR António Lugo received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Jorge Arce received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Carlos Márquez received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Keith Verstraten received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Doug Delaney received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Rodrigo Pérez becomes a free-agent. | | 3B Lane Barber received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Ricky Holland received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Héctor Ramírez received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Jim Jones received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Ricky Greenberg received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Cristián García received a 1-year contract through automatic renewal worth a total of $400,000. | | 2B Eduardo Hernández received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Brett Taylor becomes a free-agent. | | SS Gary Walsh received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Manny Lucero received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Lynn Miller becomes a free-agent. | | 2B Dan Harris becomes a free-agent. | | MR Steve Becker becomes a free-agent. | | SP Buck Gibbs becomes a free-agent. | | MR Felipe López becomes a free-agent. | | MR Pedro Silva becomes a free-agent. | | CL Cal Valcourt becomes a free-agent. | | MR Pedro Méndez becomes a free-agent. | | SS Roy Lowery becomes a free-agent. | | LF Alberto Rivera becomes a free-agent. | | Placed SS Doug Delaney on the active roster. | | Activated SS Doug Delaney from the disabled list. | | Placed 2B Eduardo Hernández on the active roster. | | Activated 2B Eduardo Hernández from the disabled list. | | LF Ryan Hankins was designated for assignment and placed on waivers. | | Released LF Patrick Gould. |
| Saturday, November 14th, 2015 | | MR Bill Johnson received a 1-year contract through arbitration worth a total of $2,065,000. | | SS Jody Bailey becomes a free-agent. | | MR Rubén Estrada becomes a free-agent. | | C Gerardo Martínez received a 1-year contract through arbitration worth a total of $600,000. | | 3B Roberto Peña received a 1-year contract through arbitration worth a total of $680,000. |
| Thursday, November 12th, 2015 | | Signed free agent C Jim Rowe to a minor league contract. |
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